LaPlace, La. -- Five people were killed early Friday when a driver going the wrong way crashed into another vehicle on Interstate 10 outside New Orleans, authorities said.
A man driving a SUV was traveling eastbound in the westbound lanes of I-10 near LaPlace when it crashed with another vehicle around 3 a.m. with four people inside, said Louisiana State Police spokesman Sgt. Len Marie.
The SUV burst into flames. All five people died at the scene.
"Everything was burned pretty bad," Marie said. "We're not sure why he was traveling the wrong way."
An 18-wheeler then sideswiped the wreck and another vehicle hit the 18-wheeler. The drivers of those vehicles suffered minor injuries, said Trooper Nick Manale.
The wreckage has been removed and all the westbound lanes of I-10 have re-opened, Marie said.
The crash was under investigation. It's not clear if the four people in the other car were related.
New Orleans TV station WWLTV reported that state police got several calls about a vehicle going the wrong way.
LaPlace is about 25 miles west of New Orleans.
Msnbc.com's Miranda Leitsinger and The Associated Press contributed to this report.